After high yields MCAT topics for biology, it’s time for biochemistry! These two topics are tested together in the same section so your challenge is to integrate your knowledge in these two areas to answer the questions correctly. For example, you will be provided with a passage about a certain disease that involves a defective protein; the questions can be about inheritance pattern, gene expression, and protein structure. Let’s take a look at these high yields topics!

1. Structures of macromolecules (carbohydrates, lipids, nucleic acids, proteins)

• Glucose structure in both straight and cyclic forms appear the most.

• Lipids might not come up as much, but do know their general structures and general properties e.g. structural vs storage lipids.

• Emphasis on the proteins, particularly the amino acids. Make sure you know their names, properties and abbreviation. Levels of proteins structures come up quite often, regarding bond types associated with each level.

• For DNA, it can be very useful if you remember the structures of A, T, C, G. Bonds types associated each level is a must know as well.

2. Enzyme kinetics

• Formulas, interpretation of Michaelis-Menten and Lineweaver-Burk plots

• Different types of enzyme inhibition and regulation 3. Gene expression and expression control

• DNA replication, transcription and translation. Know the role of different protein and enzymes involved in each process e.g. transcription factor, DNA/RNA polymerases etc.

• Operon model (induced vs repressed)

• Types of mutation e.g. silent, missense, frameshift mutations.

4. Metabolism basics (important enzymes/substrate names & functions)

• Glycolysis, especially irreversible steps • Gluconeogenic-specific enzymes

• TCA cycle enzymes and substrates in order e.g. which ones produce what byproducts

• ETC

5. Lab techniques (DNA, RNA and proteins)

• Know the main purposes and overall interpretation of the results presented.

I know it’s quite a lot for biochemistry, but if you plan out your study accordingly, I’m sure you will master your these topics soon enough before the actual MCAT exam. We still have two more subjects to go!!!

Have fun studying!

Jane